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Article
2024

A high sucrose detection threshold is associated with increased energy intake and improved post-prandial glucose response independent of the sweetness intensity of isocaloric sucrose solutions

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Several studies proposed a role for the sweet taste receptor in energy intake and blood glucose regulation, but little is yet known about the impact of the individual sweet taste perception. Here, we found in a cross-over human intervention study with 29 male participants that modulating the sweetness of an isocaloric sucrose solution did not influence postprandial plasma concentrations of blood glucose and associated hormones over 120 min and 2 h post-load energy intake. Independent of the sweetness of the test solution, tests persons with a higher sucrose detection threshold had an average of 402 ± 78.8 kcal (39 ± 21%) higher energy intake and a higher glucose/insulin ratio, combined with a higher liking for sweet tasting food, than the test persons of the low threshold group. The body composition suggested a higher fat-free mass in the high threshold group that may have influenced energy intake and post-prandial glucose responses.

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npj metabolic health and disease, 2 (2024), 1. https://doi.org/10.1038/s44324-023-00003-0. ISSN: 2948-2828 London : Nature Publishing Group UK

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Preinfalk, V., Schweiger, K., Hüller, L., Dunkel, A., Kimmeswenger, I., Deck, C. M., Rust, P., Somoza, V., Krammer, G. E., Ley, J. P., & Lieder, B. (2024). A high sucrose detection threshold is associated with increased energy intake and improved post-prandial glucose response independent of the sweetness intensity of isocaloric sucrose solutions. npj metabolic health and disease, 2. https://doi.org/10.1038/s44324-023-00003-0

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English

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610 Medicine and health

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Sustainable Development Goals

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@article{Preinfalk2024, doi = {10.1038/s44324-023-00003-0}, author = {Preinfalk, Verena and Schweiger, Kerstin and Hüller, Leonie et al.}, title = {A high sucrose detection threshold is associated with increased energy intake and improved post-prandial glucose response independent of the sweetness intensity of isocaloric sucrose solutions}, journal = {npj Metabolic Health and Disease}, year = {2024}, volume = {2}, }

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